In africa, up to 80% of the population uses traditional medicine, while in industrialized countries the market for herbal medicine is growing steadily. Abstract the phytochemical analyses, nutrient value and economic importance of hibiscus sabdariffa commonly known as zobo plant was carried out. Seventeen medicinal plants were mentioned and confirmed to possess bioactive constituents responsible for cancer therapy. Echoviruses, a serotype of enteroviruses, infect millions of people globally and there is no specific drug treatment or vaccine available for its management. It is the tradition that is of remarkable contemporary relevance. In the first century ad, dioscorides wrote a compendium of more than 500 plants that remained an authoritative reference into the 17 th century. Illness is regarded as having both natural and supernatural causes and. These plants possess good immunomodulatry and antioxidant properties leading to anticancer activity. In vitro antiviral activity of twentyseven medicinal. It has been used for relaxant and sedative purposes for thousands of years. In this study, the ethnomedicinal approach was used to select several medicinal plants native to nigeria, on the basis of their local or traditional uses. So far plants have been proved to be a novel source of useful. Mali and nigeria have created the center of traditional medicine. The effort to find anticancer agents from higher plants was launched by the us national cancer institute nci in 1957.
Traditional west african pharmacopeia, plants and derived. Newman encyclopedia of life support systems eolss reached the stage of general use. Mation published in 2012 on plant derived anticancer compounds. It is documented that medicinal herbs have rich anticancer potential, and on the forefront whenever we talk about anticancer remedies, are significant source of synthetic andor herbal origin. The problems of poor selectivity and severe side effects of the available anticancer drugs, have.
A textbook of medicinal plants from nigeria is intended to focus further interests on medicinal plants from nigeria. Jan 01, 2008 this book provides a clear understanding of the link between plants and health, and it is a useful addition to the growing literature on medicinal plants from nigeria. Ten medicinal plants used in nigerian ethno medicine were subjected to. Medicinal plants are playing an important role as a source of effective anticancer agents and it is significant that 60% of currently used anticancer agents are derived from natural sources including plants2. Exploring the nigerian medicinal plants with anticancer.
A selected number of potential anticancer agents in phytochemicals isolated from some indigenous food and. Flavonoids are from the polyphenolic compounds and constitute a large family of plant secondary metabolites with 10,000 known structures 19. The tropical rainforest of which nigeria is a part has been described by sofowora24 as a reservoir. Ethnobotanical survey of medicinal plants used in curing. Medicinal plants have been used in the treatment and prevention of some infectious diseases such as. The plants studied were phyllanthus amarus schum and thonn, euphorbia heterophylla linn. Page 6 india has one of the richest plant medical traditions in the world. The traditional healer provides health care services based on culture, religious background, knowledge, attitudes, and beliefs that are prevalent in his community.
However, there is little or no literature on the anticancer properties of medicinal plants used in ethnomedicine in nigeria. A bioactivity versus ethnobotanical survey of medicinal. Medicinal plants in nigeria were considered by several researchers gbile9 and iyamabo to form an important component of the natural wealth of the country. Based on the fact that herbal medicine is a strong component of integrative medicine, this study was conducted to evaluate the anticancer activity of root extracts of. The importance of medicinal plants, and the contribution of phytomedicine to the wellbeing of a significant number of the worlds population, has attracted interest from a variety of disciplines 5. Phytochemical and anticancer studies on ten medicinal plants. It is very likely that a phytochemical investigation of the nigerian plant species may yield maytansinoids, as is. Medicinal plants either single or in combination as a recipe. In nigeria, over 100 plants are used for the management of malaria, but little is known for their potential role in combatting.
Nigerian medicinal plants aspilia africana, bryophyllum pinnatum, garcinia kola, spondias mombim and uvaria chamea are used in herbal medicine to cure diseases, protect and regenerate liver cells, prevent alcoholic liver damage, viral liver damage and toxic liver damage. West african medicinal plants and their phytochemicals with anticancer properties. Cancer is a leading cause of death worldwide, with approximately 17. A compiled check list of these plants including their latin names, families, parts used, medicinal uses, and name in different nigerian states is the main purpose of this study. Naturally occurring anticancer compounds represent about half of the chemotherapeutic drugs which have been put in the market against cancer until date. The wellresearched writeups by renowned researchers cover a range of topics which include history, practice, and challenges of. A textbook of medicinal plants in nigeria by tolu odugbemi 628 pages unilag press. Medicinal plants are densely distributed in the tropical rainforest zones of the world of which nigeria fall into.
Because fungal and human cells are similar at a biochemical level it is often the case that chemical compounds intended for plant defence have an inhibitory effect on human cells. The collected plants were then evaluated for cytoxicity. Pdf phytochemical and anticancer studies on ten medicinal. Nigeria is richly endowed with indigenous plants, which are used in herbal medicine to cure diseases and heal injuries. List and uses of medicinal plants in nigeria in 2019 legit. Phytochemical importance of medicinal plants as potential. Many plantderived products have been reported to exhibit potent antitumor activity against several rodent and. Based on the fact that herbal medicine is a strong component of integrative medicine, this study was conducted to evaluate the anticancer activity of root. Qualitative and quantitative phytochemical screening of. The study showed that 325 species and 95 families of medicinal plants were recognized as being used by most of the people in nigeria for the treatment of various common diseases. Food and medicinal uses of the source plants have also been described. Medicinal plants, anticancer agents, bioactive compounds. Plants need to defend themselves from attack by microorganisms, in particular fungi, and they do this by producing antifungal chemicals that are toxic to fungi.
Although several medicines are available in the market to. Medicinal plants have been used for thousands of years in folk medicines in asian and african populations and many plants are consumed for their health benefits in developed nations. They are physiologically active agents in plants and becoming of high interest scientifically for their health benefits 2021 various plants have been investigated for their flavonoid content and how these compounds affect cancer. Plantderived anticancer agents in clinical use figure 1. Whole plant extracts ethanol extracted were prepared, coded as plant extract numbers 117, and tested for their potential as anticancer agents. Evaluating medicinal plants for anticancer activity.
Of over 100 plants used to treat malaria in nigeria, 56 have documented anticancer properties, containing alkaloids, flavonoids, tannins, terpenes, terpenoids, quinones, anthraquinones, saponins, steroids, sterols, organosulfur compounds and other polyphenols as the major bioactive components. Qualitative and quantitative phytochemical screening of some. Wild lettuce is a widely used medicinal plant used in traditional medicine not only in nigeria but almost every part of the world where it can be found. In nigeria, over 100 plants are used for the management of malaria, but little is known for their potential role in combatting cancer. An overview of the anticancer properties of some plants. In vitro and in vivo anticancer activity of root extracts of. The screening of medicinal plants used locally for the treatment of infectious diseases, can provide a reliable option in the discovery of potent therapeutic compounds. Ethnobotanical survey of medicinal plants used in curing some. However, as described in sections 3 to 5, a number of agents are in preclinical development. In vitro anticancer screening of 24 locally used nigerian medicinal plants saudat adamson fadeyi1,3, olugbeminiyi o fadeyi2,4, adedeji a adejumo5, cosmas okoro2 and elbert lewis myles1 abstract background. This study was carried out to investigate the antiviral activities of.
Qualitative and quantitative phytochemical screening of six plants used in ethnomedicine in the niger delta region of nigeria was carried out to identify and quantify the bioactive compounds present in these highly medicinal plants. Phytochemical analysis and medicinal uses of hibiscus sabdariffa. Anticancer potential of medicinal plants and their. Cancer, chemotherapy,cancer cells, natural products, plants, medicinal plants, herbal medicine. Exploring the nigerian medicinal plants with anticancer activities. Fabaceae has the largest number of species 42, followed by asteraceae 22, euphorbiaceae 20, acanthaceae and apocynaceae 12. Ethnobotanical survey of medicinal plants used in the. Anticancer potentials of phytochemicals from some indigenous. Medicinal plants and traditional medicine in africa traditional medicine development for medical and dental primary health care delivery system in africa. Herbal and medicinal plants molecules towards treatment of. In nigeria the plant is used to make a popular beverage known as zobo. Research and development consultant professor, phytochemistry. This paper discussed the factors responsible for, different forms of cancer, as well as organs or parts it affect.
Preparations of the plant are commonly used across nigeria for the treatment of inflammatory conditions. Seventeen medicinal plants were mentioned and confirmed to possess bioactive constituents responsible for. In vitro and in vivo anticancer activity of root extracts. In table 1 these plants are listed along with the parts used for the treatment of malaria, the parts used for anticancer studies, bioactive classescompounds, cancer cell types and the proposed mechanisms of action. Evidences have been accumulated since ages to demonstrate promising potential of medicinal plants used in various traditional, complementary, and alternative systems especially for cancer treatment. Diarrhoea is one of the common clinical signs of gastrointestinal disorders caused by both infectious and noninfectious agents and an important livestock debilitating condition. Om prakash, amit kumar, pawan kumar, and ajeet, anticancer potential of plants.
Emeritus professor of chemistry, university of ibadan, ibadan, former director, national institute for pharm. Traditionally used anticancer herbs in india article pdf available in journal of medicinal plant research. In vitro anticancer screening of 24 locally used nigerian. In conclusion this article provides the knowledge about anticancer medicinal plants of foreign origin, which are used by people all over the world. Pdf on jan 1, 2018, abdullahi danbaba abdullahi and others published exploring the nigerian medicinal plants with anticancer activities. Pdf in vitro cytotoxic activity of medicinal plants from. This book contains very interesting writeups on medicinal plants, and pictures of medicinal plants. Natural products discovered from medicinal plants have played an important role in the treatment of cancer. Many indigenous plants are used in herbal medicine to cure various diseases and heal injuries. Computerbased or in silico virtual screening methods are often used in leadhit discovery protocols. Medicinal plants are used to address the twin problems of promoting sustainable livelihoods and treatment of numerous illnesses in nigeria. There chemical compounds are formulated with a view to create effective drugs against cancer. Phytochemical analysis and medicinal uses of hibiscus. Nigeria is a country blessed with a vast flora of medicinal importance and the therapeutic potency of such plants have been demonstrated by several researchers 11, 12.
Anticancer potential of plants and natural products. Nigeria, depend on herbal medicine to meet their health care needs 10. In vitro anticancer screening of 24 locally used nigerian medicinal. In vitro cytotoxic activity of medicinal plants from. The study examined the medicinal value of forest products in the treatment of cancer in southwest nigeria. Department of biochemistry, faculty of basic medical sciences, university of medical sciences ondo, ondo state, 234, nigeria. Molecular modeling of potential anticancer agents from. Plants, animals, soils, incantationswords, spiritualism.
The paper also explored some nigerian medicinal plants with anticancer agents. Some efficacious nigerian anticancer herbal remedies joseph ibomeim okogun, phd, dic, fas, faas, frsc, fcsn, fnsp. Natural products especially plants have been used for the treatment of various diseases for. A bioactivity versus ethnobotanical survey of medicinal plants from nigeria, west africa lydia l. Nigerian antimalarial plants and their anticancer potential. Izevbigie eb discovery of watersoluble anticancer agents edotides from a vegetable found in benin city, nigeria. Phytochemical and anticancer studies on ten medicinal plants used in nigeria article pdf available july 2011 with 82 reads how we measure reads. In recent years, medicinal plants have attracted huge attention due to their diverse range of biological and therapeutic properties. Ethnobotanical studies of anticancer plants in ogun state. Herbal medicines in african traditional medicine intechopen. Sansevieria liberica gerome and labroy agavaceae is a perennial plant widely distributed in tropical africa. Anticancer and antioxidative activities of nigerian traditional. Table 2 shows the effects of nigerian antimalarial medicinal. Screening of medicinal plants native to kano and jigawa.
The search identified 56 nigerian antimalarial plants that had also been investigated for their anticancer activity. An overview of the anticancer properties of some plants used. The importance of medicinal plants, and the contribution of phytomedicine to the wellbeing of a significant number of the worlds population. Plants that are used as traditional medicine represent a relevant pool for selecting plant candidates that may have anticancer properties. In this study we have selected few medicinal plants which show high potency towards the cancer cell line by inhibiting their progression. The present study represents an attempt to document information on the traditional medicinal plants that used in nigeria.
We have also developed standards of four plants so far in the entire continent but we are taking it one step further by now having nigeria as a country propose ten plants, which have been accepted. These plants exhibit a wide range of biological and pharmacological activities such as anti cancer, antiinflammatory, diuretic, laxative, antispasmodic, antihypertensive. Screening of medicinal plants native to kano and jigawa states of northern nigeria, using artemia cysts brine shrimp test. Many of the medicinal plants, especially in nigeria have been documented 4. Also it is of significance to exploit novel anticancer drugs from medicinal plants.
Ogunyemi the village chemist, department of pharmacognosy, faculty of pharmacy, obafemi awolowo university, ileife. It is the tradition that is of remarkable contemporary relevance for ensuring health security to the teeming millions. Medicinal plants as potential source of anticancer. Pdf exploring the nigerian medicinal plants with anticancer. African traditional medicine is a form of holistic health care system organized into three levels of specialty, namely divination, spiritualism, and herbalism. Tolu odugbemi, 2008 materia medica, vegetable 628 pages. Jan 31, 2015 in recent years, medicinal plants have attracted huge attention due to their diverse range of biological and therapeutic properties. Invitro and invivo antitumor activity of catharanthus roseus. Pdf ten medicinal plants used in nigerian ethno medicine were subjected to phytochemical and anticancer studies using established. Introduction natural products especially plants have been used for the treatment of various diseases for thousands of years. Several reports describe that the anticancer activity of medicinal plants is due to the. Terrestrial plants have been used as medicines in egypt, china, india, and greece from ancient times and an impressive number of modern drugs.
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